Nanomat 4 and Capillary Dispenser
The Nanomat 4 serves for easy application of samples in the form of spots onto TLC and HPTLC layers, precisely positioned and without damage to the layer. The actual sample dosage is performed with a disposable capillary pipette, which is precisely guided, thus ensuring that the chromatogram can be scanned automatically according to a programmed pattern.
The Nanomat 4 is suitable for:
Conventional TLC plates including self-coated plates up to 20 x 20 cm
HPTLC plates 10 x 10 cm and 20 x 10 cm
TLC and HPTLC sheets up to 20 x 20 cm
The capillary pipettes are loaded into the dispenser in magazines. Capillaries of 0.5, 1, 2, and 5 μL volume are available. Each capillary size requires an appropriate dispenser magazine. With the Universal Capillary Holder capillary pipettes are taken from the dispenser, then filled with sample solution and placed against the applicator head of the Nanomat 4.
With the Linomat 5 samples are sprayed onto TLC/HPTLC plates in the form of bands with nitrogen or compressed air. Sample application is automatic, only changing the syringe (filling, inserting and rinsing) is manual. The Linomat is suitable for routine use.
The Linomat 5 is·
Operation under winCATS/visionCATS or in stand alone mode
Sample application as narrow bands using the spray-on technique
Application of solutions onto any planar medium
Semi-automatic operation, only changing of sample (cleaning, filling and replacing the syringe) is performed manually.
Automatic TLC Sampler 4 (ATS 4)
Automatic sample application is a key factor for productivity of the HPTLC laboratory. The requirements for an instrument serving this purpose, i.e. precision, robustness during routine use and convenient handling are fully met by the Automatic TLC Sampler 4. The ATS 4 offers fully automatic sample application for qualitative and quantitative analyses as well as for preparative separations. It is suited for routine use and high sample throughput in mass analysis.
Samples are either applied as spots through contact transfer (0.1–5 μL) or as bands or rectangles (0.5 to > 50 μL) using the spray-on technique. Starting zones in the form of narrow bands offer the best separation attainable with a given chromatographic system. Application in the form of rectangles allows precise application of large volumes without damaging the layer. Prior to chromatography, these rectangles are focused into narrow bands with a solvent of high elution strength. The ATS 4 allows “overspotting”, i.e. a sequential application from different vials onto the same position. This technique can be used e.g. in prechromatographic derivatization, spiking, etc.
The Automatic TLC Sampler ATS 4 with winCATS is compliant with the requirements of GMP/GLP and can be IQ/OQ qualified. If you want to use the instrument in a 21 CFR Part 11 environment, the option 21 CFR Part 11«compliance ready» is required for each winCATS workstation.